Through the years, a multitude of drug combinations and protocols for hypotensive anesthesia have been suggested and compared. The two main strategies for achieving hypotensive anesthesia are (a) deep anesthesia and heavy analgesia and (b) standard anesthesia and administration of hypotensive drugs. By deepening the anesthetic plane and using high doses of analgesics, such as opioids, the recovery time may be prolonged. On the other hand, administering a hypotensive agent to a patient who is anesthetized using a standard anesthetic protocol may result in postoperative hypotension. In practice, the two strategies are used to achieve controlled hypotensive anesthesia. In the next section, we will discuss some of the anesthetic agents, analgesics, hypotensive drugs, and nonpharmacological methods that have been used for achieving hypotensive anesthesia.